The REP is an infrastructure that links together nearly all of the medical records of the residents of Olmsted County, MN for approved medical research. This infrastructure makes it possible to conduct population-based descriptive, case-control, historical and prospective cohort, and cross-sectional research studies of most diseases and medical conditions. However, the REP is not a traditional database that can be electronically queried to ask specific research questions. Instead, the REP provides the means for collecting data to answer important research questions.

The REP has been used by hundreds of investigators for developing epidemiologic studies on a wide range of medical conditions. Since 1966, this resource has supported projects resulting in over 2,000 cumulative publications. As such, the REP continues to welcome research ideas and proposals from investigators from around the world.

• REP Population Overview: Population pyramids - Demographic, socioeconomic, and racial/ethnic characteristics.
• Current REP Research Projects: Listing of all current research projects being supported by REP data.
• Current Federally Funded REP Research Projects: Listing of NIH-funded research projects that are being supported by REP data.
• Using REP Resources for Research Studies: A FAQ for using REP data in a research project.
• Mayo Clinic Center for Translational Science Activities: The Mayo Clinic CTSA works to translate scientific discoveries into better ways of delivering health care and improving patients' health.

• Who can conduct a REP study?
• What approvals are needed to conduct a REP project?
• How do we protect individuals who participate in REP research studies?